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. 2017 Feb 6;7:42016. doi: 10.1038/srep42016

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MCF-7 and MDA-MB 231 cells treated with CAPE showed downregulation of mortalin mRNA (A) and protein (B) as compared to untreated control cells. Co-immunostaining of control and CAPE-treated cells with mortalin antibody and mito-tracker showed decrease in mortalin intensity (C). High resolution confocal laser images showed remarkable reduction in nuclear mortalin, shown by white arrows (D).