Table 2.
Amygdala peak magnitude by contrast category and diffusion parameters for white matter tracts.
| Variable | M (SD) | |||
|---|---|---|---|---|
| Trauma-exposed (n = 22) |
Control (n = 20) |
|||
| Right | Left | Right | Left | |
| Amygdala response (% signal change) | ||||
| Novel negative vs Familiar negative | 0.30 (0.58) | 0.11 (0.46)* | 0.25 (0.60) | 0.49 (0.70)* |
| Novel neutral vs Familiar neutral | 0.06 (0.60) | 0.13 (0.27) | 0.28 (0.43) | 0.30 (0.53) |
| Novel positive vs Familiar positive | 0.16 (0.73) | 0.31 (0.72) | 0.12 (0.64) | 0.45 (0.85) |
| Cingulate part of cingulum (CGC) | ||||
| FA | 0.40 (0.02) | 0.43 (0.03) | 0.38 (0.03) | 0.41 (0.04) |
| MD | 79E-05 (3E-05) | 80E-05 (3E-05) | 81E-05 (4E-05) | 83E-05 (5E-05) |
| RD | 63E-05 (3E-05) | 62E-05 (4E-05) | 65E-05(4E-05) | 66E-05 (6E-05) |
| Parahippocampal cingulum (PHC) | ||||
| FA | 0.30 (0.02) | 0.30 (0.02) | 0.29 (0.02) | 0.29 (0.01) |
| MD | 104E-05 (6E-05) | 103E-05 (6E-05) | 108E-05 (6E-05) | 103E-05 (6E-05) |
| RD | 90E-05 (7E-05) | 90E-05 (6E-05) | 96E-05 (6E-05) | 92E-05 (7E-05) |
| Uncinate fasciculus (UC) | ||||
| FA | 0.35 (0.02) | 0.35 (0.02) | 0.35 (0.02) | 0.35 (0.03) |
| MD | 85E-05 (3E-05) | 87E-05 (4E-05) | 86E-05 (3E-05) | 87E-05 (4E-05) |
| RD | 71E-05 (4E-05) | 73E-05 (4E-05) | 73E-05 (5E-05) | 73E-05 (6E-05) |
FA = Fractional anisotropy, MD = mean diffusivity, RD = radial diffusivity.
* denotes significant group difference at p < 0.05.