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. 2004 Dec 1;114(11):1686–1687.

Figure 7.

Figure 7

Glucose tolerance of syndecan-3–/– and wild-type mice. (A and C) Glucose tolerance of female (A) and male (C) syndecan-3–/– mice (n = 3) compared with wild-type mice (n = 3). Glucose (20% D-glucose) was administered intraperitoneally and tail blood samples were drawn for glucose measurements (at 0, 15, 30, 45, 60, and 120 minutes after glucose administration). The area under the curve (AUC) was calculated (using trapezoidal analysis) during the IPGTT and was compared between wild-type and syndecan-3–/– mice using a Student’s t test (*P < 0.001). (B and D) Plasma insulin was measured in female (B) and male (D) syndecan-3–/– and wild-type mice. In a second IPGTT administered identically to the first, a blood sample was drawn 15 minutes following glucose administration for analysis of plasma insulin. Insulin was compared between wild-type and syndecan-3–/– mice using a Student’s t test (#P < 0.05). No difference was seen between plasma insulin levels between female mice.