Figure 3. Effect of three-month resveratrol treatment on neointima formation, vessel size, and lumen size of rat carotid arteries following balloon injury.

(A) Representative van Gieson-stained sections from arteries treated respectively with control PCL sheaths (no resveratrol) and resveratrol-loaded sheaths and collected at 3 months after injury. Arrows indicate external elastic lamina (EEL); arrowheads mark internal elastic lamina (IEL). (B–D) Quantified data of IH (ratio of intima/media area), lumen area, and arterial remodeling (EEL length), respectively. Each bar represents a mean (±SEM) of sections from 4–5 animals, *P < 0.05 compared to vehicle control.