Results from longitudinal analyses of total cerebral volume for subgroups. (A) Total cerebral volume data for the three subgroups: ASD-DM, ASD-N, and TD boys. Each line connects the data points from each individual subject. The ASD-DM group (red) falls in the upper end of the distribution, while there is almost complete overlap between the ASD-N (green) and TD (blue) participants. (B) Individual subject data are represented as individual data points. The lines represent the predicted growth trajectories of total cerebral volume for each of the three subgroups, ASD-DM, ASD-N, and TD. ASD-DM boys had significantly greater TCV at the earliest age and also a significantly greater rate of growth from ages 3–5 years, compared to ASD-N and TD boys.