Table 2. qcrB Mutants are resistant to compounds that target the bc 1 complex.
| Fold resistance to qcrB mutant |
||||||||
| Entry | Compound | A317V | M342T | W312G | A396T | M342I | A317T | S182P |
| 1 | 5 | 46.9 | 1.4 | 46.9 | 4.1 | 6.1 | 24.5 | 15.9 |
| 2 | 9 | >250 | 3.0 | 47.0 | 3.9 | 3.9 | 23.5 | 15.7 |
| 3 | 12a | >1250 | 3.8 | 235.0 | 5.0 | 1.8 | 30.0 | 19.5 |
| 4 | 12c | 63.9 | 4.1 | 24.5 | 3.1 | 3.1 | 24.5 | 15.9 |
| 5 | 12g | 134.3 | 2.1 | 17.1 | 5.6 | 1.4 | 32.9 | 32.9 |
| 6 | 12l | >32.5 | >2 | >16.3 | >2 | 1.0 | >12.5 | >16.3 |
| 7 | 12n | >130 | >12.5 | >25 | >6.3 | >12.5 | >32.5 | >95.8 |
| 8 | 3 a | >81 | 20.2 | >81 | 20.2 | 20.2 | 10.1 | 61.3 |
| PAS a | 0.5 | 0.3 | 0.5 | 0.3 | 0.5 | 0.2 | 0.5 | |
aCompound 3 (positive control), PAS (p-aminosalicylic acid, negative control).