Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed PxaTPS8-catalyzed mechanism based on quantum chemical calculations. After cleavage of the diphosphate group of GGPP, the initial carbocation, A, forms via 1,6-cyclization. Single-step 1,2-alkyl shift and 6,10-cyclization afford a second carbocation, B, with the characteristic 5,7-fused bicyclic structure. Deprotonation of B yields pseudolaratriene.
