Fig. 7.

Infection-specific changes of the Yersinia–host transcriptomes. Schematic overview of the complex transcript-based adaptations of Y. pseudotuberculosis and the host during colonization of Peyer’s patches. The most strongly affected inflammatory and acute-phase responses, metabolic and virulence adaptations, and identified differentially regulated bacterial riboregulators with impact on pathogenesis are illustrated. DC, dendritic cell; NK, natural killer cell; NO, nitric oxide; PMN, polymorphonuclear leukocyte.