Table 5.
Toxicity in the Trial and Control Group
| Toxicity | Trial (n = 69) | Control (n = 36) | P* | ||||||||
| 0 | I | II | III | IV | 0 | I | II | III | IV | ||
| Anemia | 37 | 16 | 8 | 7 | 1 | 21 | 9 | 4 | 1 | 1 | 0.665 |
| Leukopenia | 28 | 23 | 9 | 9 | 0 | 17 | 13 | 4 | 2 | 0 | 0.570 |
| Thrombocytopia | 59 | 5 | 2 | 2 | 1 | 31 | 3 | 1 | 1 | 0 | 0.557 |
| Nausea / Vomiting | 32 | 16 | 19 | 2 | 0 | 18 | 4 | 11 | 2 | 1 | 0.476 |
| Fever | 52 | 12 | 5 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.000 |
| Eruption | 67 | 2 | 0 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.274 |
| Cold-like symptoms | 47 | 19 | 3 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.000 |
| Ostealgia / Myosalgia | 46 | 21 | 2 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.000 |
| Chill | 38 | 31 | 0 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.000 |
| Pain in injection area | 13 | 41 | 15 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.000 |
| Hardening, swelling and redness in injection area | 42 | 17 | 10 | 0 | 0 | 36 | 0 | 0 | 0 | 0 | 0.000 |
*The p value is calculated by Fisher exact chi-square because n<30 or some cells have expected count less than 1.