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G-SB2KO mice have normal insulin and glucose tolerance. (Left) Female and (Right) male for all experiments. (A) Insulin tolerance tests (ITT) were performed on 3-mo-old mice. (B) Oral-glucose tolerance tests (GTT) were performed on 8-mo-old mice and (C) intraperitoneal (IP)-GTT on 3-mo-old mice. n = 6–8 mice per group. Student’s t test *P < 0.05.
