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G-SB2KO are protected from high-fat diet. (A) Six-week-old male mice were placed on a high-fat diet for 7 wk and weighed weekly, then were placed in metabolic cages, with access to high fat diet, for 48 h and (B) RER was determined during the light and dark cycles. n = 5 per group. Student’s t test *P < 0.05, **P < 0.01.
