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. Author manuscript; available in PMC: 2017 Feb 6.
Published in final edited form as: J Am Chem Soc. 2016 Jan 21;138(4):1335–1343. doi: 10.1021/jacs.5b11742

Table 4.

Results from screening the S peptide-spiked E. coli peptide library for binding to ribonuclease S.

Early gradient
Identified features 874
Unique (– ribonuclease S) 51
Unique (+ ribonuclease S) 33
Identified hits1 4
Confirmed hits2 1
1

Hits were identified on the basis of altered hydrogen exchange using the criteria in equations (1) and (2).

2

Hits were confirmed by inspection of the extracted spectra as illustrated in Figure S3.