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. 2017 Feb 6;12(2):e0171643. doi: 10.1371/journal.pone.0171643

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© 2017 Ruskin et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — Top panels: male mice. Top left: Self-directed grooming behavior in the three-chamber test. Grooming was elevated by MIA treatment, and this effect was reversed completely by KD feeding. Post hoc tests were restricted to within-phase comparisons; n = 8–10. Top right: Self-directed behavior in the single chamber test. Grooming was elevated by MIA treatment, and this effect was partially reversed by KD feeding. **p<0.01, ***p<0.001 compared to CD-fed control offspring. ##p<0.01 compared to CD-fed MIA mice; n = 8–10. Bottom panels: female mice. Bottom left: Grooming in the three-chamber test was not elevated by MIA treatment in females; it was, however, lowered by KD feeding; n = 11–12. Bottom right: Grooming in the one-chamber test was not affected by MIA or KD in females. *p<0.05, ***p<0.001 compared to CD-fed control mice.