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(A) Activation of PAR-1 by MMP-9 (pseudo color green); n = 3. (B) Expression of pERK in HUVEC cells by MMP-9 in presence and absence of anti-PAR-1; n = 3. (C). Expression of MMP-9 and PAR-1 in aortic leaflets from patients with atherosclerosis; n = 3.
