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. 2017 Feb 6;12(2):e0171438. doi: 10.1371/journal.pone.0171438

Table 2. Ratio of clinical to chest X-ray diagnoses in various samples of children.

N Age Location Ratio of diagnoses: clinical/chest X-Ray Comments Reference
222 0-60Ma Sevagram Wardha, central India 1.05 Chest X-ray criteria were more sensitive than the WHO-EPC introduced in 2001. Gupta 1996 [34]
2,071 <21Yb Boston MA, USA 1.2 1,501 < 5 years old. Ratio is for physician rated probability of pneumonia >75%. Study conducted at Children's Hospital of Boston. Neuman 2010 [35]
155 ≤19Y Baltimore MD and Columbus OH, USA 1.4 62% < 2 years old. Grossman 1988 [36]
314 <60M Hong Kong 1.8 Hospitalized. Clinical diagnosis: bacterial, pneumonia; chest X-ray criterion: consolidation. Chiu 2014 [37]
191 <60M Orlando FL, USA 1.9 Rothrock 2001 [38]
420 2-59M Gambia (rural) 1.9 Kuti 2014 [39]
651 <24M Mozambique (rural) 2.3 Roca 2010 [40]
4,093 1-35M Bogotá, Colombia 2.4 Benavides 2012 [41]
125,983c <60M Washington, USA 2.4 Nelson 2008 [9]
100 <16Y Unugu, Nigeria 2.7 Clinical diagnostic criteria were not specified. Njeze 2011 [42]
13,026 1-35M Goiana, Brazil 2.8 Goiana, Brazil, children who presented at hospital, but were not necessarily hospitalized. Andrade 2012 [43]
1,068 <36M Northern California 2.8 “High suspicion” of pneumonia from clinical exam. (See Black [44] below for “low suspicion” pneumonia.) Black 2002 [44]
570 12M-16Y Ontario or Quebec, Canada 2.8 Study includes all who presented to hospital; 97% were not admitted. Lynch 2004 [45]
30,397d30,444e 0-17M Guatemala (rural) 2.8 Parents excluded some clinically diagnosed children from X-ray, so ratio may be artifactually large. Smith 2011 [46]
525 1M-16Y Tel Aviv, Israel 2.9 68% <6 years old. Ayalon 2013 [47]
351 ≤18M Guatemala (rural) 3.0 Children with WHO criteria for pneumonia referred to MD by field health worker for diagnosis and X-ray read by same MD. Bruce 2007 [48]
NRf <24M Refugee camp, Thailand 3.3 Cohort was 955 children. Incidence reported as cases/(child·year). Turner 2013 [49]
1,608 1-36M San Jose, Costa Rica 3.5 Prospective Surveillance of children presenting to health centers for invasive pneumococcal disease only. Arguedas 2012 [50]
413 36-60M Hong Kong 4.1 Ho 2007 [51]
1,698 <36M Northern California 4.5 “Lower suspicion” pneumonia (See Black [44] above for “high suspicion” of pneumonia). Black 2002 [44]
477 <24M Hong Kong 4.9 Ho 2007 [51]
711 0-15Y Northern England 5.0 80% < 5years old. Clark 2007 [52]
1,519 <60M Pakistan (urban) 5.8 Clinical impression was "suspicion" of pneumonia. Hazir 2006 [53]
1,622 <60M Boston MA, USA 5.9 Clinical diagnosis based on WHO tachnypea. Shah 2010 [54]
200 <60M Beer Shiva, Israel 6.1 Clinical impression was “suspicion” of pneumonia. Ben Shimol 2012 [55]
1,918 4-23M Ukraine (urban) 7.7 Pilishvili 2013 [56]

a Months.

b Years.

c Child·years of observation.

d Child weeks of observation, clinical diagnoses.

e Child weeks of observation, chest X-ray diagnoses.

f Not reported, but 488/955 (51.1%) had at least one episode.