Skip to main content
. 2017 Feb 6;12(2):e0170078. doi: 10.1371/journal.pone.0170078

Fig 1. Anti-tumor efficacy of Ab417 in a Choi-CK xenograft model.

Fig 1

Ab417 (10 mg/kg) or the isotype control (hFc, 3.3 mg/kg) was i.v. injected twice a week into nude mice bearing Choi-CK or TFK-1 xenografts (n = 8). Tumor volume (A), tumor weight (B), and body weight (C) were represented. Each point indicates the mean ± s.d. p < 0.05 (*) and p < 0.01 (**), significant difference from the isotype control group by Dunnett’s t-test. p < 0.05 (#), significant difference from the isotype control group by Steel’s test. (D) Tumor sections were stained with an anti-human Ki-67 antibody. Ki-67 index are represented as a percentage of positively-stained area comparing to total area.