Table 1. Subject characteristics from the analysis of duodenal biopsies.
| Patient/Sex | Age Years | SerologyAnti-tTG titresa | HLA status DQ2/DQ8 | IgA | Histology | Diagnose |
|---|---|---|---|---|---|---|
| E11/M | 10 | NEG | DQ8 | Normal | Normal | Non-CD |
| E12/F | 9 | NEG | -/- | Normal | Normal | Non-CD |
| E19/M | 11 | NEG | DQ2/DQ8 | Normal | Normal | Non-CD |
| E21/F | 8 | NEG | -/- | Normal | Normal | Non-CD |
| E32/F | 64 | NEG | -/- | Normal | Normal | Non-CD |
| E33/M | 19 | NEG | -/- | High | Normal | Non-CD |
| E34/F | 62 | NEG | DQ8 | Normal | Marsh 1 | Non-CD |
| E37/F | 23 | NEG | DQ2 | Normal | Normal | Non-CD |
| E39/F | 35 | NEG | DQ2/DQ8 | Normal | Normal | Non-CD |
| E43/M | 21 | POS/35 | -/- | High | Normal | Non-CD |
| E13/M | 13 | POS/22 | DQ2/DQ8 | Normal | Normal | Potential CD |
| E16/F | 14 | POS/84 | DQ2/DQ8 | Normal | Marsh 1 | Potential CD |
| E26/F | 9 | POS/78 | DQ2/DQ8 | Normal | Normal | Potential CD |
| E36/F | 59 | POS/53 | DQ2 | Normal | Marsh 1 | Potential CD |
| E14/M | 9 | POS/116 | DQ2 | Normal | Marsh 3 | CD |
| E15/M | 12 | POS/>150 | DQ2 | Normal | Marsh 3 | CD |
| E18/F | 9 | POS/34 | DQ2/DQ8 | Normal | Marsh 3 | CD |
| E20/F | 7 | POS/78 | DQ8 | Normal | Marsh 3 | CD |
| E22/F | 15 | POS/98 | DQ2 | Normal | Marsh 3 | CD |
| E31/F | 16 | POS/143 | DQ2 | Normal | Marsh 3 | CD |
| E38/F | 28 | POS/>150 | -/- (Carrier of the β-subunit of DQ2.5) | Normal | Marsh 3 | CD |
| E41/F | 21 | POS/>150 | DQ2 | Normal | Marsh 3 | CD |
| E42/F | 17 | POS/73 | DQ2 | Normal | Marsh 3 | CD |
| E45/F | 26 | POS/>150 | DQ8 | Normal | Marsh 3 | CD |
| E46/F | 22 | POS/54 | DQ2 | Normal | Marsh 3 | CD |
Table 1 shows the characteristics of the 11 CD patients, 4 potential CD patients, and 10 non-CD disease controls enrolled in the study.
aCut-off value was 20 for a positive result; maximum value was 150.