Table 6.

Patient-reported measures for HCV+ versus HCV− patients (DOPPS phases 1–5, 1996–2015): Logistic regression models

Outcome Measure (Lower=Better)	Outcome Prevalence, %	Unadjusted Odds Ratio (95% CI)a	Adjusted Odds Ratio (95% CI)b
Depressionc	44.1	1.28 (1.17 to 1.40)d	1.27 (1.16 to 1.40)d
Prurituse	40.6	1.24 (1.16 to 1.33)d	1.27 (1.18 to 1.36)d
Lack of appetitef	23.2	1.25 (1.16 to 1.35)d	1.22 (1.12 to 1.32)d

HCV+, hepatitis C virus-positive; HCV−, hepatitis C virus-negative; DOPPS, Dialysis Outcomes and Practice Patterns Study; 95% CI, 95% confidence interval.

^aAdjusted for DOPPS country (United States black and nonblack patients considered separately)and phase and accounting for facility clustering.

^bAdditionally adjusted for age, sex, time on dialysis, 13 summary comorbidities and hepatitis B infection, and albumin, phosphorus, and creatinine levels.

^cOdds ratio from a logistic model for a Center for Epidemiologic Studies Short Depression Scale (CES-D-10) score ≥10 (versus <10) for HCV+ versus HCV− patients (n=34,035 patients); not collected in DOPPS phase 1 (1996–2001).

^dP<0.05.

^eOdds ratio for moderately to extremely bothered by itchiness for HCV+ versus HCV− patients (n=52,469 patients).

^fOdds ratio for moderately to extremely bothered by lack of appetite for HCV+ versus HCV− patients (n=52,185 patients).