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. 2017 Feb 1;11:337–350. doi: 10.2147/DDDT.S121518

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© 2017 Karimian et al. This work is published and licensed by Dove Medical Press Limited

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Immunohistochemical results of apoptotic markers.

Notes: Tumor control (A), LD KME treatment (B), HD KME treatment (C) and tamoxifen treatment (D). Brown particles represent Bax, Bcl-2, p53 and caspase-3 protein expression. Microscopic observation illustrates the high expression of Bax, p53 and caspase-3 and a low expression of Bcl-2 in the HD KME- and tamoxifen-treated groups. Magnification, 100×.

Abbreviations: HD, high dose; KME, Kelussia odoratissima methanol extract; LD, low dose.