Table 1.
Characteristics | miR-17 expression
|
P-value | |
---|---|---|---|
Low (n=48), n (%) |
High (n=44), n (%) |
||
Age(years) | 1 | ||
≥50 | 21 (43.8) | 20 (45.4) | |
<50 | 27 (56.2) | 24 (54.6) | |
COX-2 | 1 | ||
Positive | 23 (47.9) | 21 (47.7) | |
Negative | 25 (52.1) | 23 (52.3) | |
CD44 | 0.68 | ||
Positive | 24 (50.0) | 24 (54.5) | |
Negative | 24 (50.0) | 20 (45.5) | |
EGFR | 0.8 | ||
Positive | 15 (42.9) | 13 (38.2) | |
Negative | 20 (57.1) | 21 (62.8) | |
ER | 0.006 | ||
Positive | 20 (41.7) | 31 (70.5) | |
Negative | 28 (58.3) | 13 (29.5) | |
PR | 0.83 | ||
Positive | 24 (50.0) | 21 (47.7) | |
Negative | 24 (50.0) | 23 (52.3) | |
HER-2 | 0.0007 | ||
Positive | 20 (41.7) | 34 (77.3) | |
Negative | 28 (58.3) | 10 (22.7) | |
PGP | 0.17 | ||
Positive | 12 (44.5) | 19 (65.5) | |
Negative | 15 (55.5) | 10 (34.5) | |
Lymph node metastasis | 0.29 | ||
Positive | 26 (54.1) | 29 (65.9) | |
Negative | 22 (45.9) | 15 (34.1) |
Abbreviations: COX-2, cyclooxygenase-2; EGFR, epidermal growth factor receptor; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2; PGP, P-glycoprotein.