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. 2016 Jun 3;36(3):e00338. doi: 10.1042/BSR20160089

Figure 3. Effects of LPA and cPA analogues on the viability of PC-3 cells.

Figure 3

(A) Effects of cPA, cPA analogues (20 μM) and LPA (10 μM) on PC-3 cells viability after 24 or 48 h incubation; ###, significantly different from methanol-treated cells (CNT) (P < 0.001). (B) Effects of cPA analogs concentration on PC-3 cell viability after 24 h; IC50 was extrapolated from the inhibition curve. (C) Effects of cPA analogues on LPA-dependent proliferation of PC-3 cells; cell viability was tested after 24 or 48 h incubation with 20 μM cPA or its analogues in the presence of 10 μM LPA; results significantly different from cells treated only with LPA were marked with *, P < 0.05 and **, P < 0.01.