Table 1. SBP (mmHg), BW (g), kidney/BW ratio (mg/g), heart/BW ratio (mg/g), GFR (ml/min), urinary albumin excretion (UAE, mg/24 h) in control, CsA and CsA+C21-treated rats at the end of 8 days of treatment.
*P<0.01 compared with control group.
| Control | CsA | CsA+C21 | |
|---|---|---|---|
| SPB, mmHg | 140.1±2.2 | 176.2±2.8* | 174.2±2.5* |
| BW, g | 384.75±13.48 | 335.16±5.51* | 341.71±8.42* |
| Kidney/BW, mg/g | 3.905±0.169 | 3.879±0.098 | 4.005±0.089 |
| Heart/BW, mg/g | 3.192±0.116 | 2.958±0.073 | 3.194±0.075 |
| GFR, ml/min | 1.716±0.241 | 1.681±0.248 | 1.663±0.262 |
| UAE, mg/24 h | 1.53±0.62 | 1.89±0.30 | 1.58±0.73 |