. Author manuscript; available in PMC: 2018 Mar 7.

Published in final edited form as: J Theor Biol. 2016 Dec 29;416:28–37. doi: 10.1016/j.jtbi.2016.12.021

Table 2.

Enzymes and fluxes represented by parameters used in the mathematical model.

Parameter	Representative Enzyme(s) or Flux	Abbreviation
p₁	methionine adenosyltransferase I	MAT-I
	methionine adenosyltransferase III	MAT-III
p₂	DNA methyltransferases	DNMT
	glycine N-methyltransferase	GNMT
p₃	S-adenosylhomocysteine hydrolase	SAHH
p₄	methionine synthase	MS
	betaine-homocysteine methyltransferase	BHMT
p₅	cystathionine β-synthase	CBS
p₆	glutamate-cysteine ligase	GCL
p₇	glutathione synthetase	GS
p₈	glutathione peroxidase	GPX
p₉	glutathione reductase	GR
f₂	SAM efflux	–
f₄	homocysteine efflux	–
f₇	GSH efflux	–