Table 2.
Baseline and three month data. Data are mean scores (SD) and differences between groups were compared by using unpaired t tests unless otherwise indicated
|
Usual care (n=16)
|
Early rehabilitation (n=18)
|
|||||
|---|---|---|---|---|---|---|
| Outcome measure | At discharge | At three months | At discharge | At three months | Mean difference between groups (95% CI) | P value |
| Shuttle walk test in metres: | ||||||
| Median distance (range) | 115 (20-190) | 90 (10-250) | 120 (10-330) | 210 (40-400) | 60 (26.6 to 93.4)* | 0.0002† |
| St George's respiratory questionnaire (range 100-0)‡: | ||||||
| Symptoms | 77.7 (14.6) | 76.8 (15.4) | 73.1 (18.2) | 69.1 (16.7) | −3.1 (−12.1 to 5.8) | 0.48 |
| Activities | 87.4 (8.7) | 84.6 (15.0) | 81.3 (15.1) | 70.5 (19.6) | −8.1 (−17.6 to 1.5) | 0.10 |
| Impacts | 56.8 (19.2) | 52.3 (16.6) | 53.7 (17.7) | 30.8 (16.9) | −18.4 (−28.7 to −8.1) | 0.001 |
| Total | 69.6 (13.5) | 66.2 (13.6) | 65.4 (14.1) | 49.3 (15.3) | −12.7 (−5.0 to −20.4) | 0.002 |
| Chronic respiratory disease questionnaire§: | ||||||
| Dyspnoea (range 5-35) | 11.4 (4.4) | 13.5 (4.3) | 11.8 (5.0) | 19.4 (5.2) | 5.5 (2.0 to 9.0) | 0.003 |
| Fatigue (range 4-28) | 11.6 (6.1) | 13.8 (5.1) | 9.9 (2.8) | 17.4 (5.4) | 5.3 (1.9 to 8.8) | 0.004 |
| Emotion (range 7-49) | 27.0 (12.6) | 29.7 (11.4) | 21.1 (5.8) | 32.5 (7.2) | 8.7 (2.4 to 15.0) | 0.008 |
| Mastery (range 4-28) | 13.6 (7.4) | 16.1 (7.0) | 10.8 (4.8) | 20.7 (5.0) | 7.5 (4.2 to 10.7) | <0.001 |
| SF-36 (range 0-100)¶: | ||||||
| Physical component | 30.4 (19.9) | 36.4 (22.2) | 26.3 (14.6) | 43.0 (20.0) | 10.6 (−0.3 to 21.6) | 0.057 |
| Mental component | 41.6 (21.9) | 47.2 (24.2) | 30.6 (14.2) | 56.3 (24.0) | 20.1 (3.3 to 36.8) | 0.02 |
| Hospital readmissions rate in % | - | 57.1 | - | 35.0 | 0.66 (0.3 to 1.5)** | 0.30†† |
| Total hospital days | - | 123 | - | 86 | - | 0.21† |
| Accident and emergency visit rate in % | - | 42.9 | - | 10.0 | 0.14 (0.03 to 0.65)** | 0.01†† |
*
Median difference.
†
Mann-Whitney test.
‡
Decreased score denotes improvement. Minimal clinically important difference is 4 points on the total score.
§
Increased score denotes improvement. Minimal clinically important difference is 2.5 (dyspnoea domain), 2 (fatigue domain), 3.5 (emotion domain) and 2 (mastery domain).
¶
Increased score denotes improvement.
**
Incident rate ratio.
††
Poisson regression.