Table 1.
Demographic and Histopathological Features of the Prospective Clinical Samples (Cohort I)
| Characteristic | n = 51 | % |
|---|---|---|
| Gender | ||
| Male | 28 | 54.9 |
| Female | 23 | 45.1 |
| Age | ||
| Median | 67 | – |
| Range | 31-85 | – |
| Tumor entities (n = 51) | ||
| Colorectal cancer | 20 | 39.2 |
| Non–small cell lung cancer | 19 | 27.3 |
| Thyroid cancer | 3 | 5.9 |
| Melanoma | 2 | 3.9 |
| Pancreatic cancer | 2 | 3.9 |
| Breast cancer | 2 | 3.9 |
| GIST | 1 | 2.0 |
| Nonmelanoma skin cancer | 1 | 2.0 |
| Erdheim Chester disease | 1 | 2.0 |
| Non–small cell lung cancer (n = 19) | ||
| Adenocarcinoma | 15 | 78.9 |
| Squamous cell carcinoma | 1 | 5.3 |
| Pleomorphic carcinoma | 1 | 5.3 |
| Combined⁎ | 1 | 5.3 |
| NOS | 1 | 5.3 |
| Primary tumor/metastasis | ||
| Primary tumor only | 32 | 62.7 |
| Metastasis only | 13 | 25.5 |
| Matched primary and metastasis | 3 | 5.9 |
| Two different primary tumors† | 3 | 5.9 |
| Nucleic acid analysis | ||
| DNA and RNA | 39 | 76.5 |
| DNA only | 12 | 23.5 |
| Tumor cell content | ||
| 10%-30% | 7 | 13.7 |
| 31%-70% | 15 | 29.4 |
| >70% | 29 | 56.9 |
⁎
Combined small cell carcinoma with adenocarcinoma and sarcoma components.
†
Two different, synchronous or metachronous primary tumors or different manifestations of the disease (for Erdheim Chester disease case) were analyzed.