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. Author manuscript; available in PMC: 2017 Feb 7.

Published in final edited form as: Free Radic Biol Med. 2014 Mar 24;71:362–367. doi: 10.1016/j.freeradbiomed.2014.03.022

Time course of hypothermia in wild type (WT) and iNOS^−/− mice induced by lipopolysaccharides (LPS). A). α-lipoic acid (LA) was given at 30 min prior to LPS injection. Animal number: WT+LA=17; WT-LA=14; iNOS^−/−+LA=10; iNOS^−/−-LA=10. B). LA or ascorbate were administered at 30 min after LPS injection. Data are expressed as means ± SEM. Animal number: WT+LA=12; WT-LA=13; iNOS^−/−+LA=10; iNOS^−/−-LA=10; and WT+ascrobate=4.

Time course of hypothermia in wild type (WT) and iNOS^−/− mice induced by lipopolysaccharides (LPS). A). α-lipoic acid (LA) was given at 30 min prior to LPS injection. Animal number: WT+LA=17; WT-LA=14; iNOS^−/−+LA=10; iNOS^−/−-LA=10. B). LA or ascorbate were administered at 30 min after LPS injection. Data are expressed as means ± SEM. Animal number: WT+LA=12; WT-LA=13; iNOS^−/−+LA=10; iNOS^−/−-LA=10; and WT+ascrobate=4.