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Persistence of (essential) domains and (essential) hypothetical proteins. (A) Persistence of orthologous proteins based on sequence similarity (red) and persistence of single domains (blue). (B) Persistence of domains present in JCVI but absent from the core of the mycoplasma species infecting tissue (green). Persistence of hypothetical proteins for 72 mycoplasma species including JCVI-Syn3.0 (red), M. mycoides capri LC (purple), and JCVI-Syn3.0 (blue).
