Figure 3.

Locomotion and anxiety-like behavior in adult rats exposed to intermittent adolescent alcohol. Number of crossings (A) and time spent in the center of the field (B) were evaluated in the open field test 1 week after the last alcohol exposure (pnd 62). Closed arm entries (C) and time spent exploring the open arms (D) were evaluated in the elevated plus-maze 2 weeks after the last alcohol exposure (pnd 69). Bars represent the mean ± SEM (8–12 animals per group). Data were analyzed by Student's t-test (Welch's correction). ^***p < 0.001 denotes significant differences compared with the control group.