Table 3.
Regions showing age effects on VTA and SNc connectivity (men and women combined).
| Volume (mm3) | Peak voxel (Z) | MNI coordinate (mm) | Side | Identified brain regions | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| VTA (positive correlation) | ||||||
| 8073 | 6.03 | 30 | 11 | −35 | R | Superior temporal gyrus |
| 4.75 | 27 | 5 | −29 | R | Parahippocampal gyrus (PHG) | |
| 6642 | 5.51 | −27 | 11 | −35 | L | Superior temporal gyrus/PHG |
| 3780 | 4.38 | −27 | −52 | −26 | R | Cerebellum |
| 1269 | 4.26 | 39 | −52 | −26 | L | Cerebellum |
| VTA (negative correlation) | ||||||
| 1215 | 3.89 | −39 | −22 | 55 | L | Central sulcus |
| 3.70 | −57 | −22 | 49 | L | Postcentral gyrus | |
| SNc (positive correlation) | ||||||
| 1809 | 5.35 | −18 | 2 | −32 | L | Superior temporal gyrus/PHG |
| 2808 | 4.77 | 27 | 11 | −38 | R | Superior temporal gyrus/PHG |
| 2106 | 4.13 | −30 | −64 | −23 | L | Cerebellum |
| 1134 | 3.79 | 54 | −49 | 40 | R | Angular gyrus |
| SNc (negative correlation) | ||||||
| None | ||||||
Note: voxel p < 0.001 uncorrected and cluster-level p < 0.05, FWE; R, right; L, left; PHG, Parahippocampal Gyrus.