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. 2017 Feb 7;8:34. doi: 10.3389/fphar.2017.00034

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Copyright © 2017 Saranya, Shilpa, Raghu and Priya.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Western blot analysis showing the levels of Akt, pAkt, PI3K, pPI3K, P³⁸MAPK, pP³⁸MAPK, JNK, and pJNK under control and MLL treated conditions. Downregulation in the expression of pPI3K, pAkt and upregulation of pp38 MAPK was noticed on treatment with MLL compared to control. A quantitative level of expression of different proteins is given in the bar diagram. Values are average of three independent experiments ± SD and ^∗p < 0.05 when compared to control.