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. 2017 Feb 7;8:53. doi: 10.3389/fimmu.2017.00053

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Copyright © 2017 Sanges, Jendoubi, Kavian, Hauspie, Speca, Crave, Guerrier, Lefèvre, Sobanski, Savina, Hachulla, Hatron, Labalette, Batteux, Dubucquoi and Launay.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interleukin (IL)-6 production by splenic B cells in phosphate-buffered saline (PBS) and HOCl mice at day 21 and day 42. (A) IL-6 mRNA levels in splenic B cells after collection and sorting, normalized to GUSB and expressed as fold changes to PBS day 21 for day-21 groups (top row), and to PBS day 42 for day-42 groups (bottom row) (n = 4–6 per group). (B) IL-6 supernatant levels after culture of splenic B cells for 48 h with various stimulation conditions [none, lipopolysaccharide (LPS), LPS + anti-CD40 antibody] at day 21 (top row) and day 42 (bottom row), expressed in picograms per milliliter (n = 6–8 per group).