Table 1.

Inclusion criteria

Criteria	Characteristics of eligible participants
1.	Male and female patients aged ≥18 years
2.	PAH diagnosed by RHC (at any time prior to baseline) with the following parameters:32
	i.	Resting mPAP≥25 mm Hg, and
	ii.	Resting PCWP or LVEDP≤15 mm Hg
3.	Stable PAH-specific medication in the preceding 3 months
4.	Female participants of childbearing potential must have a negative pregnancy test and agree to use contraception for study duration.

LVEDP, left ventricular end diastolic pressure; mPAP, mean pulmonary arterial pressure; PCWP, pulmonary capillary wedge pressure; PAH, pulmonary arterial hypertension; PVR, pulmonary vascular resistance; RHC, right heart catheterisation.