Fig. 1.

(A) Adenocarcinoma (AC)/noncancer (NC) ratio of different peptides originating from keratin 18 and (B) keratin 8. Peptides are shown as black bars positioned at their corresponding location in sequence at the horizontal axis. Error bars are S.D. of three independent experiments. Lack of an error bar indicates that a peptide was detected in one of the three experiments. Nontryptic cleavages are marked by color circles, either N-terminal (red) or C-terminal (blue). Arrows indicate the positions of nontryptic cleavage of the highest AC/NC ratio in protein regions.