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The expression of BDNF and phosphorylated TrkB in acupuncture-treated rats had been persistently enhanced after TBI. The level of BDNF at 6 h, 12 h, 48 h, 96 h, and 168 h after TBI was examined by ELISA kit (a). The phosphorylated TrkB at 48 h, 96 h, and 168 h after TBI was detected by western blot (b) and immunohistochemistry (d). (c) is the quantitative analysis of (b). Scale bar, 50 m. Acu: acupuncture. ∗P < 0.05 and ∗∗P < 0.01 versus TBI group. #P < 0.05 versus TBI group at 6 h.
