Table 1.

Observation during memantine administration.

Articles included	Positive symptoms	Negative symptoms	Cognitive symptoms	Side effects
Krivoy et al. 2008	↓	↓	×	—
Lee et al. 2012	×	×	×	—
Paraschakis 2014	×	↓	×	—
John et al. 2014	×	↓	×	—
Veerman et al. 2016	×	↓	↓	+
Omranifard et al. 2015	×	↓	×	—
Rezaei et al. 2014	×	↓	×	—
Lieberman et al. 2009	×	×	×	+
Schaefer et al. 2007	×	×	×	—
Swerdlow et al. 2016	×	×	↓	—

↓ reduction; × not evaluated/no variation; + reported; — not evaluated/not reported.