Figure 7. Immunostaining for human vascular endothelial growth factor (VEGF) and interleukin (IL)-10 reveals greater cytokine production by mesenchymal stem cells (MSC) in homing to muscle previously treated with pulsed focused ultrasound (pFUS).

(A) Relative fluorescence intensity of IL-10 or VEGF in regions-of-interest (ROI) drawn around human MSCs (n = 10 ROI from 5 mice per group). *Indicates significance (p < 0.05) by one-way ANOVA with Bonferroni correction. (B) Representative fluorescence images showing human MSCs (red) and either VEGF or IL-10 expression (green).