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. 2017 Feb 7;7:42245. doi: 10.1038/srep42245

Figure 4. Unweighted UniFrac PCoA plots showing gut microbiota beta diversity of isolator- and IVC-housed mice over three generations.

Figure 4

(a) Fecal samples from all isolator and IVC samples (i.e., P aged 7, 11 and 18 weeks, F1 aged 4, 11 and 18 weeks, and F2 aged 4 and 11 weeks) coloured per generation (b) Fecal samples from F1 mice aged 4 weeks only. F1 and F2 displayed low separation in both housing systems (Unweighted PCoA; Isolator: p = 0.008; R = 0.21. IVCs: p = 0.002; R = 0.23) (c) Fecal samples from F1 mice aged 11 weeks only. There was no significant separation of the F1 and F2 generation at 11 weeks of age in either housing system. P = parent mice inoculated at 6 weeks of age; F1 and F2 = offspring generations born with the microbiota.