Table 2.

Odds ratios (95% confidence interval) of unadjusted and adjusted (for age, smoking and BMI) cross-trait associations

	HPT	RP	MIG	CAD
HPT
adj
RP	0.88 (0.59–1.31)
adj	0.99 (0.64–1.54)
MIG	1.31 (0.99–1.73)	1.62 (1.21–2.17)
adj	1.31 (0.95–1.80)	1.68 (1.23–2.3)
CAD	2.85 (1.96–4.16)	2.03 (1.29–3.17)	2.19 (1.53–3.13)
adj	2.41 (1.56–3.73)	2.27 (1.42–3.65)	1.77 (1.19–2.63)

Calculation of odds ratios included a correction factor for familial clustering. Unadjusted odds ratios are shown above and adjusted below, for each combination of phenotypes. BMI represents body mass index, HPT hypertension, RP Raynaud's phenomenon, MIG migraine, CAD coronary artery disease.