Table 4. Multivariable analysis of factors independently associated with 1-year cause-specific mortality.
Death from colon cancer (hazard ratio (95% CI)) | Death from cardiovascular disease (hazard ratio (95% CI)) | |
---|---|---|
Age | ||
<65 | Reference | Reference |
65–74 | 1.59 (1.26–2.00) | 3.72 (2.29–6.05) |
⩾75 | 2.57 (2.09–3.16) | 7.02 (4.44–11.10) |
Postoperative complication | ||
Sepsis | 2.58 (2.13–3.11) | 2.33 (1.81–2.99) |
Pneumonia | 2.15 (1.39–3.34) | 2.37 (1.44–3.89) |
Abdominal abscess | 1.57 (1.18–2.08) | 1.19 (0.77–1.84) |
Myocardial infarction | 1.49 (1.10–2.03) | 1.59 (1.12–2.25) |
Gastrointestinal bleeding | 1.08 (0.85–1.37) | 1.42 (1.08–1.86) |
Other patient factors | ||
Comorbidities | ||
Congestive heart failure | 1.20 (1.01–1.43) | 2.38 (1.95–2.91) |
Peripheral vascular disease | 0.96 (0.74–1.24) | 1.86 (1.44–2.41) |
Renal failure | 1.11 (0.88–1.39) | 1.73 (1.35–2.21) |
Anaemia | 1.53 (1.27–1.84) | 1.03 (0.79–1.34) |
Unscheduled admission | 1.85 (1.59–2.14) | 1.51 (1.23–1.84) |
Blood transfusion | 1.16 (1.01–1.34) | 1.19 (0.98–1.44) |
Discharge to healthcare facility | 1.50 (1.29–1.75) | 2.68 (2.19–3.27) |
Oncologic factors | ||
AJCC stage | ||
I | Reference | Reference |
II | 2.14 (1.66–2.77) | 1.10 (0.89–1.37) |
III | 5.40 (4.20–6.94) | 0.97 (0.77–1.23) |
Tumour grade | ||
1 | Reference | – |
2 | 1.06 (0.78–1.42) | – |
3/4 | 2.24 (1.65–3.04) | – |
Unknown | 2.01 (1.32–3.07) | – |
Receipt of adjuvant chemotherapy | 0.66 (0.55–0.78) | – |
Operative factors | ||
Type of colectomy | ||
Right | Reference | Reference |
Left | 1.15 (1.00–1.33) | 1.04 (0.86–1.27) |
Partial | 1.30 (0.94–1.79) | 1.13 (0.74–1.73) |
Total | 1.15 (0.64–2.06) | 1.10 (0.51–2.37) |
Operative approach | ||
Open | Reference | Reference |
Minimally invasive | 0.77 (0.63–0.94) | 0.89 (0.68–1.16) |
Year of surgery | ||
2004–2005 | Reference | Reference |
2006–2007 | 0.86 (0.72–1.01) | 0.92 (0.74–1.15) |
2008–2009 | 0.92 (0.78–1.10) | 0.85 (0.67, 1.09) |
2010–2011 | 0.61 (0.50–0.76) | 0.51 (0.38–0.68) |
Surgeon factors | ||
Board-certification | ||
Surgery | Reference | Reference |
Colorectal surgery | 0.77 (0.62–0.94) | 0.82 (0.62–1.07) |
Annual colon cancer resection volume | ||
Low (1–5) | Reference | Reference |
Medium (5–10) | 0.86 (0.74–1.01) | 1.11 (0.89–1.38) |
High (>10) | 0.83 (0.71–0.98) | 1.09 (0.87–1.37) |