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. 2017 Jan 5;116(3):389–397. doi: 10.1038/bjc.2016.421

Table 4. Multivariable analysis of factors independently associated with 1-year cause-specific mortality.

  Death from colon cancer (hazard ratio (95% CI)) Death from cardiovascular disease (hazard ratio (95% CI))
Age    
 <65 Reference Reference
 65–74 1.59 (1.26–2.00) 3.72 (2.29–6.05)
 ⩾75 2.57 (2.09–3.16) 7.02 (4.44–11.10)
Postoperative complication    
 Sepsis 2.58 (2.13–3.11) 2.33 (1.81–2.99)
 Pneumonia 2.15 (1.39–3.34) 2.37 (1.44–3.89)
 Abdominal abscess 1.57 (1.18–2.08) 1.19 (0.77–1.84)
 Myocardial infarction 1.49 (1.10–2.03) 1.59 (1.12–2.25)
 Gastrointestinal bleeding 1.08 (0.85–1.37) 1.42 (1.08–1.86)
Other patient factors
Comorbidities    
 Congestive heart failure 1.20 (1.01–1.43) 2.38 (1.95–2.91)
 Peripheral vascular disease 0.96 (0.74–1.24) 1.86 (1.44–2.41)
 Renal failure 1.11 (0.88–1.39) 1.73 (1.35–2.21)
 Anaemia 1.53 (1.27–1.84) 1.03 (0.79–1.34)
Unscheduled admission 1.85 (1.59–2.14) 1.51 (1.23–1.84)
Blood transfusion 1.16 (1.01–1.34) 1.19 (0.98–1.44)
Discharge to healthcare facility 1.50 (1.29–1.75) 2.68 (2.19–3.27)
Oncologic factors
AJCC stage    
 I Reference Reference
 II 2.14 (1.66–2.77) 1.10 (0.89–1.37)
 III 5.40 (4.20–6.94) 0.97 (0.77–1.23)
Tumour grade    
 1 Reference
 2 1.06 (0.78–1.42)
 3/4 2.24 (1.65–3.04)
 Unknown 2.01 (1.32–3.07)
Receipt of adjuvant chemotherapy 0.66 (0.55–0.78)
Operative factors
Type of colectomy    
 Right Reference Reference
 Left 1.15 (1.00–1.33) 1.04 (0.86–1.27)
 Partial 1.30 (0.94–1.79) 1.13 (0.74–1.73)
 Total 1.15 (0.64–2.06) 1.10 (0.51–2.37)
Operative approach    
 Open Reference Reference
 Minimally invasive 0.77 (0.63–0.94) 0.89 (0.68–1.16)
Year of surgery    
 2004–2005 Reference Reference
 2006–2007 0.86 (0.72–1.01) 0.92 (0.74–1.15)
 2008–2009 0.92 (0.78–1.10) 0.85 (0.67, 1.09)
 2010–2011 0.61 (0.50–0.76) 0.51 (0.38–0.68)
Surgeon factors
Board-certification    
 Surgery Reference Reference
 Colorectal surgery 0.77 (0.62–0.94) 0.82 (0.62–1.07)
Annual colon cancer resection volume    
 Low (1–5) Reference Reference
 Medium (5–10) 0.86 (0.74–1.01) 1.11 (0.89–1.38)
 High (>10) 0.83 (0.71–0.98) 1.09 (0.87–1.37)