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. 2017 Feb 7;7:42004. doi: 10.1038/srep42004

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The effect of blocking programmed cell death-1 (PD-1) and programmed death ligand-1&2 (PD-L1&2) was measured by (A) cytokine production in the patients with Mycobacterium avium complex-lung disease (MAC-LD), and (B) that in the healthy subjects, and by (C) apoptosis status in PBMCs from the patients with MAC-LD stimulated using MAC (MOI 100). The Wilcoxon test was used to analyze the assays with or without blocking antibodies. TNF-α, tumor necrosis factor-alpha; IFN-γ, interferon-gamma; *0.01 ≤ p < 0.05; **p < 0.01.