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. 2017 Feb 2;100(2):364–370. doi: 10.1016/j.ajhg.2017.01.014

Figure 3.

Figure 3

Increased Sensitivity to Apoptosis in DSTYK-Null Cells

(A) Western blots of DSTYK protein levels in mouse NIH 3T3 fibroblasts transfected with non-targeting siRNA (control) or siRNA pool specifically targeted to Dstyk (Dstyksi). Graph shows percentage of total starting cells attached 9 hr after UV illumination. Values are means ± standard error of the mean (SEM). Representative of three independent experiments. ∗p < 0.05.

(B) Western blots of DSTYK protein levels in human fibroblasts isolated from healthy donors (control) or affected individual (IV-5). Graph shows percentage of total starting cells attached 9 hr after UV illumination. Values are means ± SEM. Representative of three independent experiments. ∗p < 0.05.

(C) Western blots of DSTYK protein levels in mouse keratinocytes transfected with non-targeting siRNA (control) or siRNA pool specifically targeted to Dstyk (Dstyksi). Graph shows percentage of total starting cells attached 9 hr after UV illumination. Values are means ± SEM. Representative of three independent experiments. ∗p < 0.05.

(D) Western blots of DSTYK protein levels in human keratinocytes isolated from healthy donors (control) or affected individual (IV-5). Graph shows percentage of total starting cells attached 9 hr after UV illumination. Values are means ± SEM. Representative of three independent experiments. ∗p < 0.05.

(E) Western blots of DSTYK protein levels in mouse melanocytes transfected with non-targeting siRNA (control) or siRNA pool specifically targeted to Dstyk (Dstyksi). Graph shows percentage of total starting cells attached 9 hr after UV illumination. Values are means ± SEM. Representative of three independent experiments. ∗p < 0.05.