Table 3.
Medication changes and protocol violations in first 3 months
| Arm 1 MTX or SSZ monotherapy n = 32 |
Arm 2 Combo MTX+ 6 wks prednisone n = 32 |
Arm 3 Combo MTX+ etanercept n = 30 |
|
|---|---|---|---|
| MTX dose reduction/switch to SC | 2 | 1 | 2 |
| Switch SSZ to MTX | 3/15 | NA | NA |
| Corticosteroids outside of protocol -kenacort intramuscular -prednisone orally 4-6wk |
3 2 1 |
0 0 0 |
0 0 0 |
| Intra articular corticosteroid injections | 0 | 0 | 0 |
SSZ sulphasalazine, MTX methotrexate, sc subcutaneous, IM intramuscular, NA not applicable