Table 7.
Effects of EAF on serum cytokines and liver glycogen contents in T2D rats
Groups | TNF-α (pg/ml) | IL-6 (pg/ml) | IL-1β (pg/ml) | LG (mg/g tissue) |
---|---|---|---|---|
NDC | 28.93 ± 6.48 | 89.17 ± 3.60 | 475.97 ± 20.64 | 15.57 ± 2.63 |
DC | 122.60 ± 11.93a | 171.67 ± 8.33a | 1041.73 ± 43.71a | 6.26 ± 0.67a |
D + EAF25 | 76.77 ± 12.65b | 116.94 ± 7.34b | 839.76 ± 25.63b | 10.11 ± 1.50 |
D + EAF50 | 59.10 ± 10.71b | 97.78 ± 5.59b | 590.97 ± 30.80b | 12.67 ± 1.83 |
D + GLI | 70.10 ± 4.00b | 123.06 ± 10.18b | 570.67 ± 31.71b | 11.55 ± 1.82 |
TNFα tumor necrosis factor-alpha, IL-6 interleukin-6, IL-1β interleukin-1β, LG liver glycogen, NDC non-diabetic control, DC diabetic control, D + EAF25 diabetic rats treated with ethyl acetate fraction 25 mg/kg b.w., D + EAF50 diabetic rats treated with ethyl acetate fraction 50 mg/kg b.w., D + GLI diabetic rats treated with glibenclamide 10 mg/kg b.w. Results are considered significant when p < 0.05
aCompared with NDC, bCompared with DC