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. 2017 Feb;216(2):511–525. doi: 10.1083/jcb.201609035

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© 2017 Nelms et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

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Figure 2. — Selecting candidate genes for an RNAi screen. Evaluation of how effectively different high-throughput categories of evidence recover a literature curated set of 143 epithelial trafficking genes, showing both percent coverage and fold enrichment. *, P < 0.01; **, P < 0.0001; ***, P < 10⁻¹⁰. P-values are estimated using the one-tailed Fisher’s exact test adjusted for multiple hypothesis testing by Holm’s method.