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. 2017 Feb 7;7:42126. doi: 10.1038/srep42126

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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MTT assay was done on a panel of cancer cells and shows cytotoxicity of diiodo-squaraine in the presence and absence of light. Data are expressed as a mean value ± standard deviation of three independent experiments. Diiodo-squaraine shows significant cytotoxicity in the presence of light in all cells, butshows negligible cytotoxicity in the absence of light. Here we observed maximum cytotoxicity in breast cancer cell MDA-MB-231 with an IC₅₀ value of 19.8 ± 1.7 μM and minimum cytotoxicity in normal breast cells MCF 10A.