Table 4.
Showing e-QTLS and associated phenotypes for SNPs under VDR peak significantly enriched for trait association
| Chrom | ChromStart | ChromEnd | Strand | Reference Allele | Observed Alleles | SNP under VDR peak (Lead + LD SNP) | RegulomeDB score | e-QTL (affected gene) | Associated GWAS Trait |
|---|---|---|---|---|---|---|---|---|---|
| chr4 | 38805982 | 38805983 | - | T | A/G | rs5743565 | 1b | TLR10/TLR6/TLR1 | Self-reported allergy |
| chr4 | 38784723 | 38784724 | + | T | A/T | rs10004195 | 1f | TLR6 | Helicobacter pylori serologic status |
| chr11 | 64140703 | 64140704 | + | C | C/T | rs10897487 | 1f | CCDC88/FLJ37970 | Leprosy |
| chr11 | 64140736 | 64140737 | + | G | C/G | rs475032 | 1f | CCDC88/FLJ37970 | Leprosy |
| chr12 | 56401084 | 56401085 | + | G | A/G | rs10876864 | 1f | RPS26 | Vitiligo |
Five of 42 trait-associated SNPs which were e-QTLs with RegulomeDB score 1, e-QTL gene and traits associated with these SNPs in GWAS studies are shown