Table 3.
VDR-FokI genotypes and alleles in 60 athletes, and comparison between 24 athletes with LBP episodes and 36 athletes without LBP episodes
| VDR-FokI genotype or allele | All athletes, N = 60, n (%) |
LBP, N = 24, n (%) |
No-LBP, N = 36, n (%) |
Crude OR (CI) | Crude P value | Adjusteda OR (CI) | Adjusteda P value |
|---|---|---|---|---|---|---|---|
| FF genotype | 24 (40.0) | 14 (58.3) | 10 (27.8) | 3.64 (1.22–10.8) | 0.018b | 5.78 (1.41–23.8) | 0.015 |
| Ff genotype |
34 (56.7) | 10 (41.7) | 24 (66.7) | 0.36 (0.12–1.04) | 0.056b | 0.24 (0.06–0.93) | 0.039 |
| ff genotype | 2 (3.3) | 0 (−) | 2 (5.6) | –c | –c | –c | –c |
| F allele | 82/120 (68.3) | 38/48 (79.2) | 44/72 (61.1) | 2.42 (1.04–5.61) | 0.037b | 2.55 (1.02–6.43) | 0.046 |
| f allele | 38/120 (31.7) | 10/48 (20.8) | 28/72 (38.9) | 0.41 (0.18–0.96) | 0.037b | 0.39 (0.16–0.98) | 0.046 |
aOR was adjusted by multivariate analysis for age, sex, BMI, ever smoking, exposure to vibrations, physical job demand, and weekly hours of physical exercise
bP comparison of LBP and no-LBP by two-tailed Pearson’s chi squared test
cOR not countable because one of the compared groups had zero subjects