Table 6.
Results of routine CSF analysis for MS patients
| PPMS (n = 103) | RRMS (n = 100) | Comparison statistics | |
|---|---|---|---|
| Total CSF cell count in/µl (range; SD) | 4.1 (1–43; 5.9) | 8.9 (1–47; 10.3) | p < 0.001 |
| Intrathecal IgG synthesis in % (range; SD) | 19.8 (0–75.4; 21.8) | 21.6 (0–84.3; 25.0) | n.s. |
| Intrathecal IgA synthesis in % (range; SD) | 3.8 (0–54.9; 12.6) | 2.1 (0–47.4; 7.5) | n.s. |
| Intrathecal IgM synthesis in % (range; SD) | 5.0 (0–92.4; 17.0) | 6.1 (0–88.3; 16.8) | n.s. |
| IgG index (range; SD) | 0.93 (0.45–2.83; 0.42) | 1.02 (0.23–4.0; 0.65) | n.s. |
| QIgG × 10−3 (range; SD) | 5.3 (2.0–16.9; 3.1) | 5.2 (1.0–15.8; 3.3) | n.s. |
| IgG concentration in CSF in mg/l (range; SD) | 60.7 (19.4–217.0; 42.4) | 55.9 (9.1–206.0; 39.8) | n.s. |
PPMS primary progressive multiple sclerosis, RRMS relapsing-remitting multiple sclerosis, IgG immunoglobuline G, IgA immunoglobuline A, IgM immunoglobuline M, QIgG quotient of IgG, SD standard deviation, n.s not significant. All group values are expressed as means