Table 5.
Association of altered maternal HDL-C and apoA1 with spontaneous preterm delivery: comparing the lowest quartile to other quartiles.
| Lipids in Quartiles | Cases n (%) | Controls n (%) | Model 1 AOR (95% CI) b | Model 2 AOR (95% CI) c |
|---|---|---|---|---|
| HDL-C (mmol/L) a | ||||
| <1.01 | 41 (22.4) | 98 (26.1) | 1.00 | 1.00 |
| 1.01–1.166 | 42 (23.0) | 97 (25.8) | 1.07 (0.63, 1.32) | 1.07 (0.63, 1.81) |
| 1.19–1.40 | 42 (23.0) | 99 (26.3) | 1.00 (0.60, 1.72) | 1.00 (0.59, 1.72) |
| >1.40 | 58 (31.7) | 82 (21.8) | 1.91 (1.15, 3.20) | 1.86 (1.10, 3.12) |
| ApoA1 (g/L) a | ||||
| <0.86 | 39 (21.3) | 99 (26.7) | 1.00 | 1.00 |
| 0.86–1.05 | 46 (25.1) | 92 (24.8) | 1.24 (0.73, 2.10) | 1.25 (0.74, 2.11) |
| 1.06–1.26 | 36 (19.7) | 103 (27.8) | 0.88 (0.51, 1.51) | 0.85 (0.49, 1.46) |
| >1.26 | 62 (33.9) | 77 (20.8) | 1.94 (1.16, 3.24) | 1.92 (1.15, 3.21) |
| Triglyceride (mmol/L) | ||||
| <1.05 | 40 (21.2) | 98 (24.9) | 1.00 | 1.00 |
| 1.05–1.45 | 49 (25.9) | 99 (25.2) | 1.11 (0.66, 1.85) | 1.13 (0.68, 1.89) |
| 1.46–2.11 | 50 (26.5) | 98 (24.9) | 0.99 (0.59, 1.68) | 1.02 (0.61, 1.73) |
| >2.11 | 50 (26.5) | 98 (24.9) | 1.02 (0.61, 1.72) | 1.07 (0.63, 1.82) |
| TC (mmol/L) | ||||
| <3.73 | 40 (21.2) | 94 (25.0) | 1.00 | 1.00 |
| 3.73–4.22 | 38 (20.8) | 94 (25.0) | 0.89 (0.51, 1.53) | 0.89 (0.52, 1.55) |
| 4.25–4.95 | 54 (29.5) | 94 (25.0) | 1.39 (0.83, 2.32) | 1.40 (0.84, 2.35) |
| >4.95 | 51 (27.9) | 94 (25.0) | 1.28 (0.76, 2.15) | 1.29 (0.77, 2.17) |
| LDL-C (mmol/L) | ||||
| <2.59 | 46 (25.1) | 94 (25.0) | 1.00 | 1.00 |
| 2.59–3.06 | 39 (21.3) | 94 (25.0) | 0.80 (0.47, 1.36) | 0.79 (0.47, 1.34) |
| 3.08–3.68 | 43 (23.5) | 94 (25.0) | 0.95 (0.56, 1.59) | 0.96 (0.57, 1.63) |
| >3.68 | 55 (30.1) | 94 (25.0) | 1.20 (0.73, 1.98) | 1.21 (0.73, 1.99) |
| ApoB (g/L) | ||||
| <0.78 | 47 (25.7) | 93 (24.7) | 1.00 | 1.00 |
| 0.78–0.96 | 47 (25.7) | 93 (24.7) | 1.01 (0.61, 1.67) | 1.01 (0.61, 1.67) |
| 0.97–1.12 | 41 (22.4) | 92 (24.5) | 0.77 (0.45, 1.31) | 0.80 (0.47, 1.36) |
| >1.12 | 48 (26.2) | 94 (25.0) | 0.87 (0.52, 1.46) | 0.90 (0.54, 1.52) |
AOR, adjusted odds ratio; 95% CI, 95% confidence interval; a p for trend was <0.05 for models 1 and 2; b Models were adjusted for maternal age, pre-pregnancy BMI, parity, medical payment and cigarette smoking; c Additional adjustment for maternal ethnicity (African American vs. other ethnic groups).