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. 2017 Jan 4;15(1):7. doi: 10.3390/md15010007

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© 2017 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Changes in the paw thicknesses (mm) of Wistar rats. Photographs showing a representative paw before (A) and after (B) carrageenan injection. Changes in paw thickness after pre-treatment with PD1, dexamethasone, or diclofenac (50, 20, and 20 mg/kg, respectively) (C). Results are presented as means ± SDs of n = 6 rats/group. Control: phosphate buffered saline (PBS)-injected; Carrageenan: carrageenan-injected; PD1: PD1-pretreated; Dexamethasone: dexamethasone-pretreated; Diclofenac: diclofenac-pretreated.